So I haven't looked into PyDrive2 yet, but I was able to finally get PyDrive to sync up with my Google Drive API and set DejaDup to automatic backups.
I was also able to show my Google Drive as a mounted location in Nautilus, which is extremely helpful!
Edit - Now have installed and gotten PyDrive2 functioning. Also, I think my problems may have came down to a simple chmod a+x
on my pydrive-upload code.