Well, one thing you should do is to copy any config files you want to edit to ~/.config/pipewire/ so that they persist between package updates (the default config files in /usr/share/pipewire/ are managed by the package manager and any manual changes will be overwritten on updates. I'd also caution you that the syntax of the config files is not set in stone (because PipeWire is still pre-1.0 and therefor has an unstable API/syntax) and that future PipeWire updates will likely require that you update your config files to match the new syntax.
That said, the best documentation I've been able to find for you is the Arch wiki entry on PipeWire, specifically the sections on changing the sample rate and resampling quality. These are the only real tuneables that are likely to make a noticeable difference in audio quality, and even then I'd be surprised if you could notice a difference on laptop speakers. You would want to investigate which sample rates your audio card supports and add those under allowed-rates (the goal here is that if the playback stream is using a sample rate that your audio card supports and you have PipeWire configured correctly then it will be played in passthrough mode which skips resampling. This is always the best option for audio quality).
