helpcomputer Sometimes it can happen, that a game will need some additional tweaks to run it, and the steps I've outlined aren't enough.
In that case, after you install the game, you can take a look at the Lutris install script of the game (you can view it on the Lutris website) to gain insight into the additional tweaks needed.
You use winecfg
("Wine configuration") to change some settings pertaining to the prefix, and you can use winetricks
for installing additional contents to the prefix needed for running the game (eg additional windows libraries etc).
You can access them both from the bottom bar when you click on the Wine icon.