Thanks everyone for chipping in here. I've gotten it to launch through Lutris while using Proton Experimental. After loading Experimental in Steam I was able to import it into Lutris as a runner. Then I just pointed the Lutris game at my .wine installation path (to the exe) and made sure my winecfg was set to Windows 10.
The game launches, but about 10 minutes into a prologue I saw it crash on me. I did see that there were no audio glitches like there was with Proton 5.13-4, thanks to the Experimental Proton. That said, it's still not too playable for me with the crash. I was impressed that it worked fine with my Nvidia GPU GTX Titan X. Playing on the lowest setting felt the smoothest, but the game crashed for me on medium quality.
Thanks for everyone's input!