You should be able to run it out of the box, the standard open source mesa drivers should work fine with your AMD graphics chips, although I'm not sure which one is used by the system. I'm also not sure about the Atheros wireless card, my computer uses Intel which works out of the box. You can install a live Solus environment on a USB and boot from it to play around with the system and make sure if stuff work or if they require proprietary drivers. In case you need to install drivers, which I don't recommend for your AMD graphics cards unless you need better OpenCL Support, Solus has a pretty good tool called DoFlicky or Hardware Drivers which automatically detect and give you the option to install proprietary drivers. If you're moving in from Windows remember that drivers are installed differently in Linux, you generally don't go to the manufacturer's website to download them. Use DoFlicky.
Here's some articles from the Help Center regarding installing a live environment in a USB and proprietary drivers.
https://getsol.us/articles/installation/preparing-to-install/en/
https://getsol.us/articles/hardware/proprietary-drivers/en/
I couldn't find anything regarding two AMD GPU's, you'll have to use PRIME, but here's an article from the Arch Wiki:
https://wiki.archlinux.org/index.php/PRIME
Remember that Arch Linux is a different operating system, and what applies there might not apply here. This is so you can just get familiarized with PRIME and switchable graphics.
