downhill Full disk encryption is usually a little faster and more secure. There might be confidential data in the cache, temp files, etc... It's much easier to reset some password if they are on an unencrypted partition and some malicious software may eventually be installed (like a keylogger for example) on an unencrypted partition.
Of course some of these imply to have a physical or a shell access to the machine.
The thing with security is that there is not one magical formula that will work for everyone. You have to know what you want to protect and against who to define a strategy, then you have to make a balance between security and usability.
